Body Surface Area Based Dosing (2024)

Body surface area (BSA) based dosing is a useful way to mitigate patient size variation in medication regimens. Using BSA may help prescriber's dose more optimally to improve drug efficacy, minimize drug toxicity, and account for some changes in pharmaco*kinetics depending on patient factors.

Dubois Formula for BSA Dosing

Dose = BSA Based Dose * 0.007184 * Height(cm)^0.725 * Weight(kg)^0.425.

Monteller Formula for BSA Dosing

Dose = BSA Based Dose x square root [(Height (cm) x Weight (kg)) / 3600]

Dubois D, Dubois EF.

Arch Intern Med. 1916; 17:863-871.

Mosteller RD.

NEJM. 1987; 317:1098.