CRANBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

Overview

Cranberry (Vaccinium macrocarpon) is an evergreen shrub that grows in bogs in North America. It produces dark red fruits that contain salicylic acid.

Chemicals in cranberries keep bacteria from sticking to the cells in the urinary tract. But they don't seem to be able to remove bacteria that are already stuck to these cells. This might explain why cranberry helps prevent urinary tract infections (UTIs), but doesn't help treat them.

People commonly use cranberry to prevent UTIs. Cranberry is also used for kidney stones, enlarged prostate, the common cold, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse cranberry with cramp bark, lingonberry, or uva ursi. These are sometimes also called cranberry but they are not the same.

Uses & Effectiveness ?

Possibly Effective for

  • Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs). Taking certain cranberry products by mouth seems to help prevent UTIs in adult females, children, and people at risk for developing UTIs due to certain surgeries or radiation treatment. But it doesn't seem to help people with neurogenic bladder, a condition caused by a spinal cord injury. Cranberry products do not seem prevent UTIs in elderly or pregnant people. It's important to note that while cranberry might help prevent UTIs in some people, it shouldn't be used to treat UTIs.

There is interest in using cranberry for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Cranberry is commonly consumed in foods. Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people.

Special Precautions and Warnings

When taken by mouth: Cranberry is commonly consumed in foods. Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people. Pregnancy and breast-feeding: Cranberry is commonly consumed in foods. There isn't enough reliable information to know if cranberry is safe to use in larger amounts when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Children: Cranberry is commonly consumed in foods. There isn't enough reliable information to know if cranberry is safe to use as medicine or what the side effects might be.

Aspirinallergy: Cranberries contain significant amounts of salicylic acid. Salicylic acid is similar to aspirin. Avoid drinking large quantities of cranberry juice if you are allergic to aspirin.

Diabetes: Some cranberry juice products are sweetened with extra sugar. If you have diabetes, stick with cranberry products that are sweetened with artificial sweeteners.

Kidney stones: Cranberry juice and cranberry extracts contain a large amount of a chemical called oxalate. Since oxalate is found in kidney stones, cranberry might increase the risk of kidney stones. If you have a history of kidney stones, stay on the safe side and avoid taking cranberry extract products or drinking a lot of cranberry juice.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Warfarin (Coumadin) interacts with CRANBERRY

    Warfarin is used to slow blood clotting. Cranberry might increase how long warfarin is in the body, and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. Your warfarin dose might need to be changed.

  • Atorvastatin (Lipitor) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down atorvastatin. This might increase the effects and side effects of atorvastatin. Avoid drinking large amounts of cranberry juice if you are taking atorvastatin.

  • Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CRANBERRY

    Some medications are changed and broken down by the liver. Cranberry might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Nifedipine (Procardia) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down nifedipine. Drinking cranberry juice while taking nifedipine might increase the effects and side effects of nifedipine.

    Minor Interaction

    Be watchful with this combination

  • Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CRANBERRY

    Some medications are changed and broken down by the liver. Cranberry might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Diclofenac (Voltaren, others) interacts with CRANBERRY

    Cranberry might decrease how quickly the body breaks down diclofenac. Drinking cranberry juice while taking diclofenac might increase the effects and side effects of diclofenac.

Dosing

Cranberry is commonly consumed in the diet in juices, jellies, sauces, and other foods.

As medicine, cranberry dried powder has most often been used by adults in doses of 250-1500 mg by mouth daily for up to 6 months. Cranberry extract has most often been used in doses of 120-1600 mg by mouth daily for 12 weeks. And cranberry juice drinks are often used in doses of 120-750 mL daily for up to 90 days. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circ*mstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

CRANBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

FAQs

What precautions should be taken with cranberry extract? ›

Cranberry has relatively high levels of oxalate, chemicals that may raise the risk of kidney stones in some people. If you have kidney stones, talk to your doctor before taking cranberry supplements or drinking a lot of cranberry juice. DO NOT use cranberry if you already have a UTI.

What are the side effects of cranberry? ›

Cranberry juice and cranberry extracts are likely safe for most adults. Drinking too much cranberry juice might cause some side effects such as mild stomach upset and diarrhea in some people.

What medications cannot be taken with cranberry? ›

by Drugs.com

Cranberry may increase the anticoagulant effect from blood thinners like warfarin and lead to bruising or bleeding. If you take an oral blood thinner, check with your doctor before consuming large amounts of cranberry or cranberry juice.

Are cranberry supplements safe to take everyday? ›

They are packed with antioxidants and can help reduce the frequency of urinary tract infections in some people. Also, they may promote heart health, improve blood sugar control, boost immunity and protect against cancer, cavities and stomach ulcers. Dosages of up to 1,500 mg per day are safe for most.

Can you flush your kidneys with cranberry juice? ›

Kidney stones are a common disorder, affecting around 1 in 11 adults in the United States ( 1 ). While there are many causes of kidney stones, diet plays a major role. In particular, cranberry juice is thought to help get rid of kidney stones, similarly to how it reduces incidence of urinary tract infections (UTIs).

What organ is cranberry good for? ›

Cranberries provide a good source of various vitamins and antioxidants. Historically, Native Americans used cranberries as a treatment for bladder and kidney diseases, while early settlers from England used them to treat poor appetite, stomach complaints, blood disorders, and scurvy.

What do cranberries do to your body? ›

Cranberries have two big benefits for heart health: lowering blood pressure and improving cholesterol. Some studies suggest that drinking low-calorie cranberry juice regularly can raise HDL (good) cholesterol and lower LDL (bad) cholesterol.

Is it safe to eat cranberries everyday? ›

Cranberries and cranberry products are usually safe for most people if consumed in moderation. However, excessive consumption may cause stomach upset and diarrhea — and may also increase the risk of kidney stones in predisposed individuals.

Does cranberry affect blood pressure? ›

Drink cranberry juice. In a 2012 study, researchers found that drinking cranberry juice regularly can help drop blood pressure (both systolic and diastolic) by three points. It might not sound like a lot, but it's enough to bump someone from pre-hypertension back into the normal range, for example.

Can I take Tylenol with cranberry? ›

Interactions between your drugs

No interactions were found between cranberry and Tylenol Cold + Mucus Severe.

Is cranberry hard on the liver? ›

There have been no convincing reports of serum enzyme elevations, jaundice or clinically apparent liver injury associated with cranberry use. Likelihood score: E (unlikely cause of clinically apparent liver injury).

Are cranberry pills safe for kidneys? ›

Some studies have suggested that cranberry juice may lower levels of a protein called cystatin C, which is a marker of kidney function. Other studies have shown that cranberry supplements improved kidney function in people with early-stage kidney disease.

Which is better, cranberry juice or cranberry pills? ›

Studies have pointed out that due to the added sugars and water that dilute the cranberry juice, cranberry capsules are a more effective alternative. In fact, it turns out that the active ingredient in cranberries that helps prevent E. coli from turning into an infection may not even be present in cranberry juice!

Does cranberry extract affect blood pressure? ›

Cranberry extracts may also help with cancer protection, teeth and gum health, lower blood pressure, obesity, and inflammation.

Should cranberry extract be taken with or without food? ›

Although cranberry extract can be taken on an empty stomach, it is recommended that the capsules are taken alongside meals, especially ones that contain another source of vitamin C, as this will help to augment the absorption of the polyphenol qualities that people are seeking.

Does cranberry extract interfere with antibiotics? ›

Analyses showed that the cranberry extract increases bacterial sensitivity to antibiotics by acting in two ways. First, it makes the bacterial cell wall more permeable to the antibiotic, and second, it interferes with the mechanism used by the bacteria to pump out the antibiotic.

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